The premier online source for science news since 1996. A service of the American Association for the Advancement of Science.
Updated: 1 year 30 weeks ago
(University of Chicago Medical Center) In the July 14 edition of Scientific Reports (Nature), 39 researchers from 14 leading institutions in the United States, United Kingdom and France suggest novel approaches that could hasten the development of better medications for people suffering from toxoplasmosis.
(Duke University) A single brain receptor is responsible for a range of symptoms in mice that are reminiscent of obsessive-compulsive disorder, according to a Duke University study appearing in the journal Biological Psychiatry. The findings suggest that OCD and other psychiatric disorders could be amenable to treatment using a class of drugs that is already being investigated in clinical trials.
(Baylor College of Medicine) Researchers at Baylor College of Medicine who focus on bronchopulmonary dysplasia and pulmonary hypertension, a common lung disease in premature infants, have shown that echocardiography can be used to detect the pulmonary hypertension in neonatal mice at an earlier time point than previously thought. Their report appears today in the International Journal of Chronic Obstructive Pulmonary Disease.
(Colorado State University) It has a funny name -- coxsackievirus -- but there's nothing funny about how this tiny germ and its close relatives sicken their hosts. Colorado State University researchers led by Professor Olve Peersen have designed a genetic modification to one type of coxsackievirus that strips its ability to replicate, mutate and cause illness. They hope their work could lead to a vaccine for this and other viruses like it.
(University of Illinois at Chicago) Researchers and physicians have grappled with the role of 'adjuvant,' or post-surgery, chemotherapy for patients with early-stage colon cancer, even for cancers considered high risk. Now researchers from the University of Illinois at Chicago have found an association between the use of adjuvant chemotherapy in stage 2 colon cancer and improved survival -- regardless of a patient's age or risk, or even of the specific chemotherapy administered. The findings are published in the journal Cancer.
(University of Pennsylvania School of Medicine) Would having your exercise performance compared to that of your peers motivate you do more? A new study suggests it might. And adding a financial incentive would only sweeten the deal even more. Comparing performance to average peers (the 50th percentile), and offering financial incentives was the most effective method for increasing physical activity among teams of employees.
(European Centre for Disease Prevention and Control (ECDC) ) Zika virus is mainly transmitted to humans through mosquitoes but can potentially also be transmitted through substances of human origin (SoHO) such as blood, tissue and cells. This new guide offers a set of activities that should be considered in the preparation and implementation of a national preparedness plan for the safety of SoHO.
(Damon Runyon Cancer Research Foundation) The Damon Runyon Cancer Research Foundation named seven new Damon Runyon Clinical Investigators at its spring 2016 Clinical Investigator Award Committee review. The recipients of this prestigious three-year award are outstanding early career physician-scientists conducting patient-oriented cancer research at major research centers under the mentorship of the nation's leading scientists and clinicians.
(University of Massachusetts Medical School) Using a systems-biology approach, scientists at the University of Massachusetts Medical School made a startling discovery that immune system signaling can directly affect, and even change, social behavior in mice and other model animals. Published in Nature, these findings could have great implications for neurological diseases such as autism-spectrum disorders and schizophrenia.
(Helmholtz Zentrum München - German Research Center for Environmental Health) Scientists at the Helmholtz Zentrum München have developed a new mass spectrometry imaging method which, for the first time, makes it possible to analyze hundreds of metabolites in fixed tissue samples. Their findings, published in the journal Nature Protocols, explain the new access to metabolic information, which will offer previously unexploited potential for tissue-based research and molecular diagnostics.
(American Academy of Sleep Medicine) A new study found a six-fold increase in the age-adjusted prevalence of any sleep disorder diagnosis over an 11-year period among US veterans. The largest increases were identified in patients with post-traumatic stress disorder (PTSD), other mental disorders, or combat experience. Results also show that the prevalence of PTSD tripled during the study period.
(European Molecular Biology Laboratory) A new type of HIV drug currently being tested works in an unusual way, scientists in the Molecular Medicine Partnership Unit, a collaboration between EMBL and Heidelberg University Hospital, have found. They also discovered that when the virus became resistant to early versions of these drugs, it did not do so by blocking or preventing their effects, but rather by circumventing them. The study, published online today in Science, presents the most detailed view yet of part of the immature form of HIV.
(Future Science Group) Future Science Group today announced the publication of a new article in Future Science OA synthesizing current data on sarcopenic obesity, and looking to highlight the need for public health strategies for prevention and treatment.
(Bentham Science Publishers) The purpose of the study was to investigate the nonlinear dynamic properties of neural ensemble activity in the primary visual cortex of rats.
(University of Veterinary Medicine -- Vienna) Microorganisms, among them fungi, are a natural and rich source of antibiotic compounds. A team from the Vetmeduni Vienna and the University of Natural Resources and Life Sciences, Vienna succeeded for the first time in extracting the rare compound cPM from a filamentous fungus, applying a special method. Using this substance leads to increased susceptibility of a resistant pathogen against standard antibiotics. The results were published in the journal Frontiers in Microbiology.
(University of Copenhagen - Niels Bohr Institute) The human body is controlled by electrical impulses in the brain, the heart and nervous system. These electrical signals create tiny magnetic fields, which doctors could use to diagnose various diseases, for example diseases of the brain or heart problems in young fetuses. Researchers from the Niels Bohr Institute have now succeeded in developing a method for extremely precise measurements of such ultra-small magnetic fields with an optical magnetic field sensor. The results are published in the scientific journal, Scientific Reports.
(IOS Press) The Journal of Alzheimer's Disease is pleased to announce that Mark W. Bondi, Ph.D., ABPP/CN, has been chosen as the recipient of the 2016 Alzheimer Award presented by the journal in recognition of his outstanding work on the development of a novel and promising method of staging preclinical Alzheimer's disease (AD) based on number of abnormal biomarkers that is predictive of progression to mild cognitive impairment and AD.
(Bentham Science Publishers) In this review, the current state of knowledge in designing pharmacologically active small molecules to possess physicochemical properties sufficient to engender blood-brain barrier penetration is examined.
(University of Erlangen-Nuremberg) Food chemists at Friedrich-Alexander-Universität Erlangen-Nürnberg have found that garlic aroma is evident in the breast milk of women who have consumed garlic. This is caused by allyl methyl sulfide -- a metabolite which is first formed in a strong concentration during breastfeeding. Whether the aroma has an impact on which food preferences children develop and whether they like garlic in later life needs to be clarified by further research.
(Allen Institute) Researchers at the Allen Institute for Brain Science have published an in-depth analysis of a comprehensive molecular atlas of brain development in the non-human primate. This analysis uncovers features of the genetic code underlying brain development in our close evolutionary relative, while revealing distinct features of human brain development by comparison.